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  • TREM2 Antibodies

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TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Monoclonal Antibody (TREM2/7210)

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Datasheet
Protocols
Questions & Answers

Cite TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Monoclonal Antibody (TREM2/7210)

  • Antibody Testing Data (2)
TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Antibody (54209-MSM1-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with TREM2 Mouse Monoclonal Antibody (TREM2/7210). Inset: PBS instead of primary antibody; secondary only negative control. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Monoclonal Antibody (TREM2/7210)

Product Details

54209-MSM1-P0

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

TREM2/7210

Immunogen

Recombinant fragment (around aa1-200) of human TREM2 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; TREM-2; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a

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Gene Aliases: TREM-2; TREM2; Trem2a; Trem2b; Trem2c

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UniProt ID: (Human) Q9NZC2

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Entrez Gene ID: (Human) 54209

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Function(s)
lipopolysaccharide binding receptor activity peptidoglycan binding lipoteichoic acid binding scaffold protein binding
Process(es)
positive regulation of antigen processing and presentation of peptide antigen via MHC class II phagocytosis, engulfment humoral immune response detection of lipopolysaccharide detection of peptidoglycan innate immune response positive regulation of peptidyl-tyrosine phosphorylation regulation of immune response positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan dendritic cell differentiation positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of CD40 signaling pathway
It has to be done as per old AB suggested Products section.
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