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  • TREM2 Antibodies

Invitrogen

TREM2 Recombinant Rabbit Monoclonal Antibody (1L3A2)

View all (35) TREM2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite TREM2 Recombinant Rabbit Monoclonal Antibody (1L3A2)

  • Antibody Testing Data (1)
TREM2 Antibody in Western Blot (WB)
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TREM2 Antibody in Western Blot (WB)
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TREM2 Antibody (MA5-51494) in WB

Western blot analysis of TREM2 in Mouse heart. Samples were incubated with TREM2 Recombinant monoclonal antibody (Product # MA5-51494) using a dilution of 1:8,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TREM2 Antibody in Western Blot (WB)

Product Details

MA5-51494

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:9,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1L3A2

Immunogen

Recombinant protein of human TREM2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.69 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093112

Target Information

TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; TREM-2; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c

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Gene Aliases: TREM-2; Trem2; Trem2a; Trem2b; Trem2c

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UniProt ID: (Mouse) Q99NH8

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Entrez Gene ID: (Mouse) 83433

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Function(s)
lipopolysaccharide binding transmembrane signaling receptor activity protein binding peptidoglycan binding lipoteichoic acid binding scaffold protein binding
Process(es)
positive regulation of antigen processing and presentation of peptide antigen via MHC class II signal transduction lipopolysaccharide-mediated signaling pathway detection of lipopolysaccharide detection of peptidoglycan innate immune response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan dendritic cell differentiation positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of CD40 signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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