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  • Primary Antibodies ›
  • TREM2 Antibodies

Fabgennix

TREM2 Polyclonal Antibody, FITC

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite TREM2 Polyclonal Antibody, FITC

TREM2 Polyclonal Antibody, FITC

Product Details

TREM2-FITC

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:200
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids within region 100-200 on mouse TREM2 protein.
View immunogen

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer with 20% glycerol, 0.5% BSA

Contains

0.01% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

Product Specific Information

Quantity: 100 µg IgG per vial

Target Information

TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; TREM-2; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c

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Gene Aliases: TREM-2; Trem2; Trem2a; Trem2b; Trem2c

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UniProt ID: (Mouse) Q99NH8

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Entrez Gene ID: (Rat) 301227, (Mouse) 83433

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Function(s)
lipopolysaccharide binding peptidoglycan binding lipoteichoic acid binding scaffold protein binding transmembrane signaling receptor activity protein binding
Process(es)
positive regulation of antigen processing and presentation of peptide antigen via MHC class II detection of lipopolysaccharide detection of peptidoglycan positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan dendritic cell differentiation positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of CD40 signaling pathway signal transduction lipopolysaccharide-mediated signaling pathway innate immune response
It has to be done as per old AB suggested Products section.
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