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Proteintech
TREM1 Polyclonal Antibody
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Product Details
11791-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MRKTRLWGL LWMLFVSELR AATKLTEEKY ELKEGQTLDV KCDYTLEKFA SSQKAWQIIR DGEMPKTLAC TERPSKNSHP VQVGRIILED YHDHGLLRVR MVNLQVEDSG LYQCVIYQPP KEPHMLFDRI RLVVTKGFSG TPGSNENSTQ NVYKIPPTTT KALCPLYTSP RTVTQAPPKS TADVSTPDSE INLTNVTDII RVPVFNIVIL LAGGFLSKSL VFSVLFAVTL RSFVP (1-234 aa encoded by BC017773)
Target Information
TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; TREM-1; triggering receptor expressed in monocytes 1; Triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Gene Aliases: CD354; TREM-1; TREM1
UniProt ID: (Human) Q9NP99, (Mouse) Q9JKE2
Entrez Gene ID: (Human) 54210, (Mouse) 58217
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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