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Invitrogen
TRAIL-R4 Polyclonal Antibody
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FIGURE: 1 / 1
TRAIL-R4 Antibody (PA5-89612) in WB
Product Details
PA5-89612
Species Reactivity
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Conjugate
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Product Specific Information
Immunogen sequence: VLFRRRSCPS RVPGAEDNAR NETLSNRYLQ PTQVSEQEIQ GQELAELTGV TVELPEEPQR LLEQAEAEGC QRRRLLVPVN DADSADISTL LDASATLEEG HAKETIQDQL VGSEKLFYEE DEAGSATSCL; Positive Samples: 22Rv1, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD264; DcR2; Decoy receptor 2; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Gene Aliases: CD264; DCR2; TNFRSF10D; TRAIL-R4; TRAILR4; TRUNDD; UNQ251/PRO288
UniProt ID: (Human) Q9UBN6
Entrez Gene ID: (Human) 8793
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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