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  • TNFR2 Antibodies

Abnova

TNFRSF1B Polyclonal Antibody, MaxPab™

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Questions & Answers

Cite TNFRSF1B Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (1)
TNFRSF1B Antibody in Western Blot (WB)
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TNFRSF1B Antibody in Western Blot (WB)
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TNFRSF1B Antibody (H00007133-B01P) in WB

Western Blot analysis of TNFRSF1B expression in transfected 293T cell line by TNFRSF1B MaxPab polyclonal antibody. Lane 1: TNFRSF1B transfected lysate(50.71 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TNFRSF1B Antibody in Western Blot (WB)
TNFRSF1B Polyclonal Antibody, MaxPab™

Product Details

H00007133-B01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TNFRSF1B (NP_001057.1, 1 a.a. approximately 461 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MAPVAVWAAL AVGLELWAAA HALPAQVAFT PYAPEPGSTC RLREYYDQTA QMCCSKCSPG QHAKVFCTKT SDTVCDSCED STYTQLWNWV PECLSCGSRC SSDQVETQAC TREQNRICTC RPGWYCALSK QEGCRLCAPL RKCRPGFGVA RPGTETSDVV CKPCAPGTFS NTTSSTDICR PHQICNVVAI PGNASMDAVC TSTSPTRSMA PGAVHLPQPV STRSQHTQPT PEPSTAPSTS FLLPMGPSPP AEGSTGDFAL PVGLIVGVTA LGLLIIGVVN CVIMTQVKKK PLCLQREAKV PHLPADKARG TQGPEQQHLL ITAPSSSSSS LESSASALDR RAPTRNQPQA PGVEASGAGE ARASTGSSDS SPGGHGTQVN VTCIVNVCSS SDHSSQCSSQ ASSTMGDTDS SPSESPKDEQ VPFSKEECAF RSQLETPETL LGSTEEKPLP LGVPDAGMKP S

Target Information

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD120b; p75; p75 TNF receptor; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TNF-R2; TNF-RII; TNFR; TNFR II; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily, member 1B; Tumor necrosis factor receptor type II

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Gene Aliases: CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; TNFRSF1B

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UniProt ID: (Human) P20333

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Entrez Gene ID: (Human) 7133

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Function(s)
tumor necrosis factor-activated receptor activity protein binding ubiquitin protein ligase binding
Process(es)
inflammatory response immune response multicellular organism development aging intrinsic apoptotic signaling pathway in response to DNA damage tumor necrosis factor-mediated signaling pathway regulation of cell proliferation regulation of apoptotic process positive regulation of MAPK cascade negative regulation of inflammatory response RNA destabilization positive regulation of membrane protein ectodomain proteolysis cellular response to lipopolysaccharide cellular response to growth factor stimulus apoptotic signaling pathway extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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