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Invitrogen

TNFR2 Recombinant Rabbit Monoclonal Antibody (7S1K0)

View all (37) TNFR2 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite TNFR2 Recombinant Rabbit Monoclonal Antibody (7S1K0)

  • Antibody Testing Data (2)
TNFR2 Antibody in Western Blot (WB)
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TNFR2 Antibody in Western Blot (WB)
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TNFR2 Antibody (MA5-35276) in WB

Western blot analysis of TNFR2 in extracts of various cell lines. Samples were incubated with TNFR2 Monoclonal antibody (Product # MA5-35276) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TNFR2 Antibody in Western Blot (WB)
TNFR2 Antibody in Western Blot (WB)
TNFR2 Recombinant Rabbit Monoclonal Antibody (7S1K0)

Product Details

MA5-35276

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7S1K0

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 362-461 of human TNFR2/TNFRSF1B (P20333)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849178

Product Specific Information

Immunogen sequence: RASTGSSDSS PGGHGTQVNV TCIVNVCSSS DHSSQCSSQA SSTMGDTDSS PSESPKDEQV PFSKEECAFR SQLETPETLL GSTEEKPLPL GVPDAGMKPS

Target Information

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD120b; p75; p75 TNF receptor; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TNF-R2; TNF-RII; TNFR; TNFR II; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily, member 1B; Tumor necrosis factor receptor type II

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Gene Aliases: CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; TNFRSF1B

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UniProt ID: (Human) P20333

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Entrez Gene ID: (Human) 7133

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Function(s)
tumor necrosis factor-activated receptor activity protein binding ubiquitin protein ligase binding
Process(es)
inflammatory response immune response multicellular organism development aging intrinsic apoptotic signaling pathway in response to DNA damage tumor necrosis factor-mediated signaling pathway regulation of cell proliferation regulation of apoptotic process positive regulation of MAPK cascade negative regulation of inflammatory response RNA destabilization positive regulation of membrane protein ectodomain proteolysis cellular response to lipopolysaccharide cellular response to growth factor stimulus apoptotic signaling pathway extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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