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  • TMLHE Antibodies

Invitrogen

TMLHE Polyclonal Antibody

View all (6) TMLHE antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite TMLHE Polyclonal Antibody

  • Antibody Testing Data (1)
TMLHE Antibody in Western Blot (WB)
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TMLHE Antibody in Western Blot (WB)
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TMLHE Antibody (PA5-21461) in WB

Western Blot using TMLHE Polyclonal Antibody (Product # PA5-21461). Sample (30 µg of whole cell lysate). A: HeLa S3. 12% SDS PAGE. TMLHE Polyclonal Antibody (Product # PA5-21461) diluted at 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TMLHE Antibody in Western Blot (WB)

Product Details

PA5-21461

Applications
Tested Dilution
Publications

Western Blot (WB)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human TMLHE. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

6.68 mg/mL

Purification

Protein A

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11154377

Product Specific Information

Recommended positive controls: H1299, HeLaS3, HepG2.

Predicted reactivity: Mouse (95%), Rat (92%), Chicken (91%), Bovine (95%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 2; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML dioxygenase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; Trimethyllysine dioxygenase, mitochondrial

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Gene Aliases: AUTSX6; BBOX2; TMLD; TMLH; TMLHE; TMLHED; XAP130

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UniProt ID: (Human) Q9NVH6

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Entrez Gene ID: (Human) 55217

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Function(s)
iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding trimethyllysine dioxygenase activity
Process(es)
carnitine biosynthetic process oxidation-reduction process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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