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  • TMLHE Antibodies

Proteintech

TMLHE Polyclonal Antibody

3 References
View all (6) TMLHE antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite TMLHE Polyclonal Antibody

  • Antibody Testing Data (3)
TMLHE Antibody in Western Blot (WB)
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TMLHE Antibody in Western Blot (WB)
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TMLHE Antibody (16621-1-AP) in WB

Mouse heart tissue were subjected to SDS PAGE followed by western blot with 16621-1-AP (TMLHE antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TMLHE Antibody in Western Blot (WB)
TMLHE Antibody in Western Blot (WB)
TMLHE Antibody in Western Blot (WB)
TMLHE Polyclonal Antibody

Product Details

16621-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TMLHE Fusion Protein Ag9919 (1-376 aa encoded by BC025269)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MWYHRLSHL HSRLQDLLKG GVIYPALPQP NFKSLLPLAV HWHHTASKSL TCAWQQHEDH FELKYANTVM RFDYVWLRDH CRSASCYNSK THQRSLDTAS VDLCIKPKTI RLDETTLFFT WPDGHVTKYD LNWLVKNSYE GQKQKVIQPR ILWNAEIYQQ AQVPSVDCQS FLETNEGLKK FLQNFLLYGI AFVENVPPTQ EHTEKLAERI SLIRETIYGR MWYFTSDFSR GDTAYTKLAL DRHTDTTYFQ EPCGIQVFHC LKHEGTGGRT LLVDGFYAAE QVLQKAPEEF ELLSKVPLKH EYIEDVGECH NHMIGIGPVL NIYPWNKELY LIRLFKEKQN TVNRQWNSSL QCDIPERILT YRHFVSGTSI EHRGSLI (1-376 aa encoded by BC025269)

Target Information

This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 2; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 2 (gamma-butyrobetaine hydroxylase); Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML dioxygenase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; TMLD; Trimethyllysine dioxygenase, mitochondrial

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Gene Aliases: AUTSX6; BBOX2; D430017M14Rik; TMLD; TMLH; TMLHE; TMLHED; XAP130

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UniProt ID: (Human) Q9NVH6, (Rat) Q91ZW6, (Mouse) Q91ZE0

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Entrez Gene ID: (Human) 55217, (Rat) 170898, (Mouse) 192289

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Function(s)
iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding trimethyllysine dioxygenase activity oxidoreductase activity metal ion binding dioxygenase activity
Process(es)
carnitine biosynthetic process oxidation-reduction process negative regulation of oxidoreductase activity
It has to be done as per old AB suggested Products section.
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