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  • TIMP2 Antibodies

OriGene

TIMP2 Monoclonal Antibody (OTI1A6), TrueMAB™

1 Reference
View all (68) TIMP2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite TIMP2 Monoclonal Antibody (OTI1A6), TrueMAB™

  • Antibody Testing Data (11)
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 11

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TIMP2 Antibody (TA504017) in IHC (P)

Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-TIMP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA504017) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TIMP2 Antibody in Western Blot (WB)
TIMP2 Antibody in Flow Cytometry (Flow)
TIMP2 Antibody in Flow Cytometry (Flow)
TIMP2 Monoclonal Antibody (OTI1A6), TrueMAB™

Product Details

TA504017

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-

Flow Cytometry (Flow)

1:100
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1A6

Immunogen

Full length human recombinant protein of human TIMP2 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated
  • Biotin 
  • Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CSC-21K; Metalloproteinase inhibitor 2; testicular secretory protein Li 57; TIMP 2; TIMP-2; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase-2; Tissue inhibitor of metalloproteinases 2

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Gene Aliases: CSC-21K; D11Bwg1104e; DDC8; Timp-2; TIMP2

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UniProt ID: (Dog) Q9TTY1, (Human) P16035, (Rat) P30121

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Entrez Gene ID: (Dog) 403633, (Human) 7077, (Rat) 29543, (Mouse) 21858

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Function(s)
protease binding metalloendopeptidase inhibitor activity metal ion binding integrin binding protein binding enzyme activator activity enzyme inhibitor activity peptidase inhibitor activity
Process(es)
response to hormone negative regulation of endopeptidase activity response to cytokine negative regulation of catalytic activity negative regulation of membrane protein ectodomain proteolysis spermatogenesis central nervous system development aging negative regulation of cell proliferation regulation of cAMP metabolic process regulation of Rap protein signal transduction response to drug positive regulation of catalytic activity regulation of MAPK cascade positive regulation of MAPK cascade regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of adenylate cyclase activity negative regulation of proteolysis negative regulation of mitotic cell cycle negative regulation of Ras protein signal transduction cellular response to organic substance extracellular matrix disassembly negative regulation of peptidase activity
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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