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Invitrogen
TIMP1 Monoclonal Antibody (C8)
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FIGURE: 1 / 2
TIMP1 Antibody (MA5-51017) in WB
Product Details
MA5-51017
Species Reactivity
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Target Information
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Collagenase inhibitor 16C8 fibroblast; EPA; Erythroid-potentiating activity; FLJ90373; Metalloproteinase inhibitor; Metalloproteinase inhibitor 1; MMP inhibitor; RP1-230G1.3; TIMP 1; TIMP-1; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase-1; Tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1
Gene Aliases: Clgi; EPA; Timp; TIMP-1; Timp1; TPA-S1
UniProt ID: (Rat) P30120, (Mouse) P12032
Entrez Gene ID: (Rat) 116510, (Mouse) 21857
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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