Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • TGF alpha Antibodies

Invitrogen

TGF alpha Monoclonal Antibody (D20)

View all (37) TGF alpha antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TGF alpha Monoclonal Antibody (D20)

  • Antibody Testing Data (2)
TGF alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
TGF alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 2

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

TGF alpha Antibody (MA5-43705) in IHC (P)

Immunohistochemistry of TGF alpha in paraffin-embedded human Glioma tissue. Samples were incubated in monoclonal TGF alpha antibody (Product # MA5-43705) using a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG at a dilution of 2 µg/mL and DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

TGF alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TGF alpha Antibody in Western Blot (WB)
TGF alpha Monoclonal Antibody (D20)

Product Details

MA5-43705

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-3 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

D20

Immunogen

Glu24-Ala98 (Accession P01135), with N-terminal His Tag
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912637

Target Information

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Protransforming growth factor alpha; TGF a; TGF α; TGF-alpha; TGFalpha; TGFα; Transforming growth factor; transforming growth factor, alpha

View more View less

Gene Aliases: RATTGFAA; TFGA; TGFA; TGFAA

View more View less

UniProt ID: (Human) P01135, (Rat) P01134

View more View less

Entrez Gene ID: (Human) 7039, (Rat) 24827

View more View less

Function(s)
epidermal growth factor receptor binding protein binding growth factor activity glycoprotein binding
Process(es)
activation of MAPK activity ER to Golgi vesicle-mediated transport cell proliferation positive regulation of epidermal growth factor-activated receptor activity positive regulation of mitotic nuclear division COPII vesicle coating positive regulation of epithelial cell proliferation positive regulation of cell division angiogenesis epidermal growth factor receptor signaling pathway positive regulation of cell proliferation wound healing response to drug negative regulation of apoptotic process negative regulation of cellular process mammary gland alveolus development
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-55c564d944-rwwh4:80/100.66.128.142:80.
git-commit: 3092084cb0e494f0e07f07633350183de7fa10a8
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0