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  • TFIP11 Antibodies

Proteintech

TFIP11 Polyclonal Antibody

View all (9) TFIP11 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TFIP11 Polyclonal Antibody

  • Antibody Testing Data (5)
TFIP11 Antibody in Immunocytochemistry (ICC/IF)
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TFIP11 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 5

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TFIP11 Antibody (14436-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 14436-1-AP (TFIP11 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TFIP11 Antibody in Immunocytochemistry (ICC/IF)
TFIP11 Antibody in Western Blot (WB)
TFIP11 Antibody in Western Blot (WB)
TFIP11 Antibody in Western Blot (WB)
TFIP11 Antibody in Western Blot (WB)
TFIP11 Polyclonal Antibody

Product Details

14436-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TFIP11 Fusion Protein Ag5821 (492-837 aa encoded by BC033080)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IVTQWQPRN CDPMVDFLDS WVHIIPVWIL DNILDQLIFP KLQKEVENWN PLTDTVPIHS WIHPWLPLMQ ARLEPLYSPI RSKLSSALQK WHPSDSSAKL ILQPWKDVFT PGSWEAFMVK NIVPKLGMCL GELVINPHQQ HMDAFYWVID WEGMISVSSL VGLLEKHFFP KWLQVLCSWL SNSPNYEEIT KWYLGWKSMF SDQVLAHPSV KDKFNEALDI MNRAVSSNVG AYMQPGAREN IAYLTHTERR KDFQYEAMQE RREAENMAQR GIGVAASSVP MNFKDLIETK AEEHNIVFMP VIGKRHEGKQ LYTFGRIVIY IDRGVVFVQG EKTWVPTSLQ SLIDMAK (492-837 aa encoded by BC033080 )

Target Information

Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Septin and tuftelin-interacting protein 1; STIP-1; Tuftelin-interacting protein 11; tuftelin-interacting protein 33; Tuftelin-interacting protein 39; tuftelin-interacting protein, 39 kD

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Gene Aliases: 2810002G02Rik; AF097181; AW046167; bK445C9.6; hNtr1; HSPC006; NTR1; Spp382; Srr1; STIP; TFIP11; TIP33; TIP39

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UniProt ID: (Human) Q9UBB9, (Rat) Q5U2Y6, (Mouse) Q9ERA6

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Entrez Gene ID: (Human) 24144, (Rat) 288718, (Mouse) 54723

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Function(s)
DNA binding protein binding nucleic acid binding
Process(es)
spliceosomal complex disassembly mRNA splicing, via spliceosome regulation of transcription, DNA-templated RNA processing biomineral tissue development negative regulation of protein complex assembly protection from non-homologous end joining at telomere negative regulation of protein binding negative regulation of DNA ligase activity negative regulation of double-strand break repair via nonhomologous end joining mRNA processing RNA splicing cell differentiation extracellular matrix organization
It has to be done as per old AB suggested Products section.
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