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  • TET3 Antibodies

Invitrogen

TET3 Polyclonal Antibody

View all (32) TET3 antibodies

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Datasheet
Protocols
Questions & Answers

Cite TET3 Polyclonal Antibody

  • Antibody Testing Data (2)
TET3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TET3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TET3 Antibody (PA5-116026) in IHC (P)

Immunohistochemistry analysis of TET3 in human pancreatic cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-116026) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TET3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TET3 Antibody in Western Blot (WB)
TET3 Polyclonal Antibody

Product Details

PA5-116026

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TET3(Accession O43151), corresponding to amino acid residues S799-C849.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900660

Product Specific Information

Antibody detects endogenous levels of total TET3.

Target Information

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3

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Gene Aliases: B430006D22Rik; BC037432; CXXC10; D230004J03Rik; hCG_40738; KIAA0401; TET3

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UniProt ID: (Human) O43151, (Mouse) Q8BG87

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Entrez Gene ID: (Human) 200424, (Rat) 680576, (Mouse) 194388

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Function(s)
DNA binding protein binding metal ion binding methylcytosine dioxygenase activity molecular_function oxidoreductase activity dioxygenase activity
Process(es)
protein O-linked glycosylation biological_process DNA demethylation of male pronucleus positive regulation of transcription from RNA polymerase II promoter oxidation-reduction process DNA demethylation histone H3-K4 trimethylation multicellular organism development chromatin modification
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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