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Proteintech

TERF1 Monoclonal Antibody (1D10G4)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TERF1 Monoclonal Antibody (1D10G4)

  • Antibody Testing Data (1)
TERF1 Antibody in Western Blot (WB)
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TERF1 Antibody in Western Blot (WB)
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TERF1 Antibody (67592-1-IG) in WB

K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TERF1 Antibody in Western Blot (WB)

Product Details

67592-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:3,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1D10G4

Immunogen

TERF1 Fusion Protein Ag12540

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1000 µg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; telomeric repeat binding factor 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1

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Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1

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UniProt ID: (Human) P54274, (Mouse) P70371

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Entrez Gene ID: (Human) 7013, (Rat) 297758, (Mouse) 21749

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Function(s)
DNA binding double-stranded telomeric DNA binding telomerase activity protein binding DNA binding, bending telomeric DNA binding protein homodimerization activity ubiquitin binding G-rich strand telomeric DNA binding molecular_function chromatin binding microtubule binding protein heterodimerization activity
Process(es)
telomere maintenance telomere maintenance via telomerase mitotic nuclear division negative regulation of DNA replication telomere capping telomeric loop formation negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via semi-conservative replication response to drug meiotic telomere clustering cell division negative regulation of telomerase activity positive regulation of telosome assembly negative regulation of establishment of protein localization to telomere negative regulation of establishment of RNA localization to telomere negative regulation of establishment of macromolecular complex localization to telomere G2/M transition of mitotic cell cycle obsolete age-dependent telomere shortening mitotic spindle assembly checkpoint obsolete telomere maintenance via telomere shortening positive regulation of microtubule polymerization positive regulation of apoptotic process positive regulation of mitotic nuclear division positive regulation of mitotic cell cycle protein homooligomerization cell cycle
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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