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Abnova
TAF11 Monoclonal Antibody (3D3)
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Product Details
H00006882-M01
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
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Purification
Storage buffer
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Product Specific Information
Sequence of this protein is as follows: SKVFVGEVVE EALDVCEKWG EMPPLQPKHM REAVRRLKSK GQIPNSKHKK IIF
Target Information
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: TAF(II)28; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; TAFII-28; TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD; TATA box binding protein associated factor 11; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; Transcription initiation factor TFIID 28 kDa subunit; Transcription initiation factor TFIID subunit 11
Gene Aliases: MGC:15243; PRO2134; TAF11; TAF2I; TAFII28
UniProt ID: (Human) Q15544
Entrez Gene ID: (Human) 6882
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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