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  • Primary Antibodies ›
  • Syntrophin alpha-1 Antibodies

Invitrogen

Syntrophin alpha-1 Polyclonal Antibody

View all (36) Syntrophin alpha-1 antibodies

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Datasheet
Protocols
Questions & Answers

Cite Syntrophin alpha-1 Polyclonal Antibody

  • Antibody Testing Data (5)
Syntrophin alpha-1 Antibody in Immunocytochemistry (ICC/IF)
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Syntrophin alpha-1 Antibody in Immunocytochemistry (ICC/IF)
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Syntrophin alpha-1 Antibody (PA5-114307) in ICC/IF

Immunocytochemical analysis of Syntrophin alpha-1 in SW620 cells using a Syntrophin alpha-1 polyclonal antibody (Product #PA5-114307). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody for 1 hour at room temperature, washed with PBS. Alexa Flu... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Syntrophin alpha-1 Antibody in Immunocytochemistry (ICC/IF)
Syntrophin alpha-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Syntrophin alpha-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Syntrophin alpha-1 Antibody in Western Blot (WB)
Syntrophin alpha-1 Antibody in Flow Cytometry (Flow)
Syntrophin alpha-1 Polyclonal Antibody

Product Details

PA5-114307

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within mouse Syntrophin alpha 1 aa 174-223
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2890509

Target Information

Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; Alpha-1-syntrophin; alpha1-syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); Syntrophin-1; TACIP1

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Gene Aliases: AW228934; dJ1187J4.5; LQT12; SNT1; SNTA1; TACIP1

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UniProt ID: (Human) Q13424

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Entrez Gene ID: (Human) 6640, (Mouse) 20648, (Rat) 362242

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Function(s)
actin binding structural molecule activity protein binding calmodulin binding sodium channel regulator activity PDZ domain binding ion channel binding nitric-oxide synthase binding ATPase binding
Process(es)
regulation of heart rate muscle contraction regulation of ventricular cardiac muscle cell membrane repolarization ventricular cardiac muscle cell action potential negative regulation of peptidyl-cysteine S-nitrosylation regulation of sodium ion transmembrane transport regulation of vasoconstriction by circulating norepinephrine neuromuscular junction development biological_process
It has to be done as per old AB suggested Products section.
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