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  • Syntrophin alpha-1 Antibodies

Invitrogen

Syntrophin alpha-1 Polyclonal Antibody

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  • Antibody Testing Data (1)
Syntrophin alpha-1 Antibody in Western Blot (WB)
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Syntrophin alpha-1 Antibody in Western Blot (WB)
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Syntrophin alpha-1 Antibody (PA1-32071) in WB

Western Blot analysis of Syntrophin alpha-1 was performed by loading 35 µg (in RIPA buffer) of human muscle lysates with (B) and without (A) blocking with the immunising peptide. Proteins were transferred to a membrane and probed with a Syntrophin alpha-1 Polyclonal Antibody (Product # PA1-32071) at a dilution of 0.01 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Syntrophin alpha-1 Antibody in Western Blot (WB)
Syntrophin alpha-1 Polyclonal Antibody

Product Details

PA1-32071

Applications
Tested Dilution
Publications

Western Blot (WB)

1-3 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence ASGRRAPRTGLLE-C, from the N Terminus.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2191799

Product Specific Information

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX25941-PEP)..



Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; Alpha-1-syntrophin; alpha1-syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); Syntrophin-1; TACIP1

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Gene Aliases: AW228934; dJ1187J4.5; LQT12; SNT1; SNTA1; TACIP1

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UniProt ID: (Human) Q13424

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Entrez Gene ID: (Human) 6640, (Mouse) 20648, (Rat) 362242

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Function(s)
actin binding structural molecule activity protein binding calmodulin binding sodium channel regulator activity PDZ domain binding ion channel binding nitric-oxide synthase binding ATPase binding
Process(es)
regulation of heart rate muscle contraction regulation of ventricular cardiac muscle cell membrane repolarization ventricular cardiac muscle cell action potential negative regulation of peptidyl-cysteine S-nitrosylation regulation of sodium ion transmembrane transport regulation of vasoconstriction by circulating norepinephrine neuromuscular junction development biological_process
It has to be done as per old AB suggested Products section.
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