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  • CD138 (Syndecan-1) Antibodies

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Syndecan-1 Polyclonal Antibody

View all (80) CD138 (Syndecan-1) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Syndecan-1 Polyclonal Antibody

  • Antibody Testing Data (1)
Syndecan-1 Antibody in Western Blot (WB)
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Syndecan-1 Antibody in Western Blot (WB)
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Syndecan-1 Antibody (SYND1-101AP) in WB

WB of SYND1-101AP with PC-SYND1 (A) and T47D cells (B). 1:500 antibody dilution in DiluOBuffer. Apparent MW is 55 kDa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Syndecan-1 Antibody in Western Blot (WB)
Syndecan-1 Polyclonal Antibody

Product Details

SYND1-101AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-100 on human Syndecan-1 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; sCD138; soluble CD138; SYND1; syndecan proteoglycan 1; Syndecan-1; Syndecan1; synstatin

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Gene Aliases: AA408134; AA409076; CD138; HSPG; SDC; SDC1; Sstn; syn-1; Synd; Synd-1; SYND1; SYNDECA; Syndecan

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UniProt ID: (Human) P18827, (Mouse) P18828, (Rat) P26260

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Entrez Gene ID: (Human) 6382, (Mouse) 20969, (Rat) 25216

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Function(s)
glycoprotein binding protein binding protein C-terminus binding extracellular matrix binding
Process(es)
retinoid metabolic process ureteric bud development glycosaminoglycan biosynthetic process glycosaminoglycan catabolic process inflammatory response response to toxic substance cell migration glycosaminoglycan metabolic process wound healing lipoprotein metabolic process odontogenesis response to hydrogen peroxide myoblast development response to glucocorticoid response to cAMP response to calcium ion striated muscle cell development Sertoli cell development canonical Wnt signaling pathway positive regulation of exosomal secretion positive regulation of extracellular exosome assembly cell adhesion cell-cell signaling response to organic substance
It has to be done as per old AB suggested Products section.
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