Bioss

Scavenger receptor class B member 1 Polyclonal Antibody

View all (26) SR-BI antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

BS-1186R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Flow Cytometry (Flow)

1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Chicken, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human CD36L1, amino acids 21-100.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen-like 1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; HDL QTL 1; scavanger receptor class B type 1; scavenger receptor b1; Scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SR-BI; SRB1

View more View less

Gene Aliases: AI120173; CD36; CD36L1; CLA-1; CLA1; D5Ertd460e; Hdlq1; HDLQTL6; Hlb398; mSR-BI; SCARB1; SR-B1; SR-BI; SRB1; SRBI

View more View less

UniProt ID: (Human) Q8WTV0, (Rat) P97943, (Mouse) Q61009

View more View less

Entrez Gene ID: (Human) 949, (Rat) 25073, (Mouse) 20778

View more View less

Function(s)
lipopolysaccharide binding virus receptor activity phosphatidylserine binding lipopolysaccharide receptor activity transporter activity protein binding 1-phosphatidylinositol binding high-density lipoprotein particle binding low-density lipoprotein particle binding apolipoprotein binding apolipoprotein A-I binding protein homodimerization activity high-density lipoprotein particle receptor activity lipid transporter activity
Process(es)
endothelial cell proliferation steroid biosynthetic process androgen biosynthetic process cholesterol catabolic process lipid transport receptor-mediated endocytosis phagocytosis, recognition cell adhesion positive regulation of triglyceride biosynthetic process positive regulation of cholesterol storage regulation of phosphatidylcholine catabolic process phospholipid transport lipopolysaccharide transport cholesterol transport lipopolysaccharide-mediated signaling pathway detection of lipopolysaccharide cholesterol efflux high-density lipoprotein particle remodeling low-density lipoprotein particle clearance high-density lipoprotein particle clearance vitamin transmembrane transport cholesterol homeostasis blood vessel endothelial cell migration recognition of apoptotic cell reverse cholesterol transport adhesion of symbiont to host regulation of phagocytosis positive regulation of nitric-oxide synthase activity triglyceride homeostasis cholesterol import pattern recognition receptor signaling pathway positive regulation of endothelial cell migration wound healing lipoprotein metabolic process viral entry into host cell intestinal absorption
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support