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  • SPG7 Antibodies

OriGene

SPG7 Monoclonal Antibody (OTI1C1), TrueMAB™

View all (36) SPG7 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SPG7 Monoclonal Antibody (OTI1C1), TrueMAB™

  • Antibody Testing Data (7)
SPG7 Antibody in Immunocytochemistry (ICC/IF)
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SPG7 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 7

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SPG7 Antibody (TA504424) in ICC/IF

Anti-SPG7 mouse monoclonal antibody (TA504424) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPG7(RC206340). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SPG7 Antibody in Immunocytochemistry (ICC/IF)
SPG7 Antibody in Immunocytochemistry (ICC/IF)
SPG7 Antibody in Western Blot (WB)
SPG7 Antibody in Western Blot (WB)
SPG7 Antibody in Western Blot (WB)
SPG7 Antibody in Flow Cytometry (Flow)
SPG7 Antibody in Flow Cytometry (Flow)
SPG7 Monoclonal Antibody (OTI1C1), TrueMAB™

Product Details

TA504424

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1C1

Immunogen

Human recombinant protein fragment corresponding to amino acids 300-573 of human SPG7 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cell adhesion regulator; Cell matrix adhesion regulator; Mitochondrial inner membrane m-AAA protease component paraplegin; Paraplegin; paraplegin, isoform 1; spastic paraplegia 7 (pure and complicated autosomal recessive); Spastic paraplegia 7 protein

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Gene Aliases: AI452278; AU015315; CAR; CMAR; PGN; SPG5C; SPG7

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UniProt ID: (Human) Q9UQ90, (Mouse) Q3ULF4, (Rat) Q7TT47

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Entrez Gene ID: (Human) 6687, (Dog) 489657, (Mouse) 234847, (Rat) 353231

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Function(s)
ATP-dependent peptidase activity metalloendopeptidase activity protein binding ATP binding peptidase activity zinc ion binding unfolded protein binding nucleotide binding metallopeptidase activity hydrolase activity metal ion binding molecular_function
Process(es)
proteolysis mitochondrion organization cell adhesion nervous system development anterograde axonal transport regulation of cell adhesion biological_process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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