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  • Primary Antibodies ›
  • Syntrophin alpha-1 Antibodies

OriGene

SNTA1 Monoclonal Antibody (OTI2E12), TrueMAB™

View all (36) Syntrophin alpha-1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SNTA1 Monoclonal Antibody (OTI2E12), TrueMAB™

  • Antibody Testing Data (4)
SNTA1 Antibody in Immunocytochemistry (ICC/IF)
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SNTA1 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 4

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SNTA1 Antibody (CF502040) in ICC/IF

Anti-SNTA1 mouse monoclonal antibody (TA502040) Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SNTA1 Antibody in Immunocytochemistry (ICC/IF)
SNTA1 Antibody in Western Blot (WB)
SNTA1 Antibody in Western Blot (WB)
SNTA1 Antibody in Flow Cytometry (Flow)
SNTA1 Monoclonal Antibody (OTI2E12), TrueMAB™

Product Details

CF502040

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Dog, Human, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI2E12

Immunogen

Full length human recombinant protein of human SNTA1 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; Alpha-1-syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); Syntrophin-1; TACIP1

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Gene Aliases: dJ1187J4.5; LQT12; SNT1; SNTA1; TACIP1

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UniProt ID: (Human) Q13424

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Entrez Gene ID: (Human) 6640, (Dog) 485837, (Rat) 362242

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Function(s)
actin binding structural molecule activity protein binding calmodulin binding sodium channel regulator activity PDZ domain binding ion channel binding nitric-oxide synthase binding ATPase binding
Process(es)
regulation of heart rate muscle contraction regulation of ventricular cardiac muscle cell membrane repolarization ventricular cardiac muscle cell action potential negative regulation of peptidyl-cysteine S-nitrosylation regulation of sodium ion transmembrane transport regulation of vasoconstriction by circulating norepinephrine neuromuscular junction development biological_process
It has to be done as per old AB suggested Products section.
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