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  • SNRNP70 Antibodies

Invitrogen

SNRNP70 Recombinant Rabbit Monoclonal Antibody (2W1C8)

View all (8) SNRNP70 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SNRNP70 Recombinant Rabbit Monoclonal Antibody (2W1C8)

  • Antibody Testing Data (2)
SNRNP70 Antibody in Western Blot (WB)
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SNRNP70 Antibody in Western Blot (WB)
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SNRNP70 Antibody (MA5-55557) in WB

Western blot analysis of lysates from wild type (WT) and SNRNP70 knockdown (KD) 293T cells using SNRNP70 Recombinant Monoclonal Antibody (Product # MA5-55557) at 1:3,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SNRNP70 Antibody in Western Blot (WB)
SNRNP70 Antibody in Western Blot (WB)
SNRNP70 Recombinant Rabbit Monoclonal Antibody (2W1C8)

Product Details

MA5-55557

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2W1C8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 201-300 of SNRNP70.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.88 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

RRID

AB_3667796

Product Specific Information

Immunogen Sequence: RGGADVNIRH SGRDDTSRYD ERPGPSPLPH RDRDRDRERE RRERSRERDK ERERRRSRSR DRRRRSRSRD KEERRRSRER SKDKDRDRKR RSSRSRERAR

Target Information

SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: small nuclear ribonucleoprotein 70kDa (U1); small nuclear ribonucleoprotein, U1 70kDa subunit; U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa

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Gene Aliases: 2700022N21Rik; 3200002N22Rik; AI325098; R74807; RNPU1Z; Rnu1p70; Rnulp70; RPU1; Snp1; SNRNP70; SNRP70; Srnp70; U1-70; U1-70K; U170K; U1AP; U1AP1; U1RNP

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UniProt ID: (Human) P08621, (Mouse) Q62376

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Entrez Gene ID: (Human) 6625, (Mouse) 20637

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Function(s)
nucleotide binding RNA binding mRNA binding protein binding U1 snRNA binding poly(A) RNA binding
Process(es)
mRNA splicing, via spliceosome mRNA processing RNA splicing regulation of ATPase activity regulation of RNA splicing positive regulation of mRNA splicing, via spliceosome negative regulation of protein refolding negative regulation of chaperone-mediated autophagy
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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