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  • SMPD2 Antibodies

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SMPD2 Monoclonal Antibody (2C9)

View all (7) SMPD2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite SMPD2 Monoclonal Antibody (2C9)

  • Antibody Testing Data (2)
SMPD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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SMPD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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SMPD2 Antibody (H00006610-M01) in IHC (P)

Immunoperoxidase of monoclonal antibody to SMPD2 on formalin-fixed paraffin-embedded human lymph node. Antibody concentration is 3 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SMPD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SMPD2 Antibody in ELISA (ELISA)
SMPD2 Monoclonal Antibody (2C9)

Product Details

H00006610-M01

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL
-

ELISA (ELISA)

10 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

2C9

Immunogen

SMPD2 (AAH00038.1, 1 a.a. approximately 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MKPNFSLRLR IFNLNCWGIP YLSKHRADRM RRLGDFLNQE SFDLALLEEV WSEQDFQYLR QKLSPTYPAA HHFRSGIIGS GLCVFSKHPI QELTQHIYTL NGYPYMIHHG DWFSGKAVGL LVLHLSGMVL NAYVTHLHAE YNRQKDIYLA HRVAQAWELA QFIHHTSKKA DVVLLCGDLN MHPEDLGCCL LKEWTGLHDA YLETRDFKGS EEGNTMVPKN CYVSQQELKP FPFGVRIDYV LYKAVSGFYI SCKSFETTTG FDPHSGTPLS DHEALMATLF VRHSPPQQNP SSTHGPAERS PLMCVLKEAW TELGLGMAQA RWWATFASYV IGLGLLLLAL LCVLAAGGGA GEAAILLWTP SVGLVLWAGA FYLFHVQEVN GLYRAQAELQ HVLGRAREAQ DLGPEPQPAL LLGQQEGDRT KEQ

Target Information

Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; NSMA; Sphingomyelin phosphodiesterase 2; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

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Gene Aliases: ISC1; NSMASE; NSMASE1; SMPD2

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UniProt ID: (Human) O60906

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Entrez Gene ID: (Human) 6610

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Function(s)
sphingomyelin phosphodiesterase activity metal ion binding
Process(es)
sphingomyelin metabolic process glycosphingolipid metabolic process response to mechanical stimulus intracellular signal transduction ceramide biosynthetic process positive regulation of ceramide biosynthetic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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