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Invitrogen
SMAD5 Polyclonal Antibody
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Product Details
PA5-89580
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
RRID
Product Specific Information
Immunogen sequence: STYPNSPASS GPGSPFQLPA DTPPPAYMPP DDQMGQDNSQ PMDTSNNMIP QIMPSISSRD VQPVAYEEPK HWCSIVYYEL NNRVGEAFHA SSTSVLVDGF T
Positive Samples: SKOV3, MCF-7, Mouse kidney; Cellular Location: Cytoplasm, Nucleus
Target Information
SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DKFZp781C1895; DKFZp781O1323; Dwarfin-C; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5
Gene Aliases: 1110051M15Rik; AI451355; Dwf-C; DWFC; JV5-1; MADH5; Msmad5; MusMLP; SMAD5
UniProt ID: (Human) Q99717, (Mouse) P97454, (Rat) Q9R1V3
Entrez Gene ID: (Human) 4090, (Mouse) 17129, (Rat) 59328
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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