Invitrogen

SLN Monoclonal Antibody (14G1A12)

Name: SLN Monoclonal Antibody (14G1A12)
Brand: Invitrogen
SKU: MA5-50293

View all (3) SLN antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

SLN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 2

SLN Antibody (MA5-50293) in IHC (P)

Immunohistochemistry analysis with a SLN monoclonal antibody (Product # MA5-50293) using a dilution of 1:60 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was... View More

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Immunogen image

Immunogen Image SLN Monoclonal Antibody (14G1A12)

Product Details

MA5-50293

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Flow Cytometry (Flow)

1:50-1:200

ELISA (ELISA)

Assay-dependent

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

14G1A12

Immunogen

Recombinant Human SLN protein (1-31AA)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.13 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_3091049

Target Information

SLN, also named as Sarcolipin, belongs to the sarcolipin family. It is associated with calcium ATPase SERCA1. It inhibits SERCA pumps. SLN, a key regulator of cardiac sarco (endo)plasmic reticulum (SR) Ca(2+) ATPase, is predominantly expressed in atria and mediates beta-adrenergic responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Sarcolipin

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Gene Aliases: SLN

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UniProt ID: (Human) O00631

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Entrez Gene ID: (Human) 6588

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Function(s)

enzyme inhibitor activity protein binding ATPase binding

Process(es)

calcium ion transport negative regulation of catalytic activity negative regulation of protein complex disassembly regulation of calcium ion transport sarcoplasmic reticulum calcium ion transport negative regulation of calcium ion import negative regulation of calcium ion transmembrane transporter activity regulation of relaxation of muscle negative regulation of calcium ion binding positive regulation of protein depolymerization regulation of calcium-transporting ATPase activity

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SLN Monoclonal Antibody (14G1A12)

SLN Antibody (MA5-50293) in IHC (P)

Product Details

MA5-50293

Immunohistochemistry (Paraffin) (IHC (P))

Flow Cytometry (Flow)

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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