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  • Primary Antibodies ›
  • SLC7A8 Antibodies

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SLC7A8 Polyclonal Antibody

1 Reference
View all (27) SLC7A8 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SLC7A8 Polyclonal Antibody

Product Details

OSS00266W-100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:2,000
-

Immunohistochemistry (IHC)

1:300-1:2,000
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from internal region of human SLC7A8 (LAT2) conjugated to an immunogenic carrier protein was used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in mouse and rat.

Specificity of this antibody: SLC7A8.

Target Information

SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re)absorption of neutral amino acids.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: cationic amino acid transporter y+ system; hLAT2; integral membrane protein E16H; L-type amino acid transporter 2; Large neutral amino acids transporter small subunit 2; mLAT2; solute carrier family 7 (amino acid transporter light chain, L system), member 8; solute carrier family 7 (amino acid transporter, L-type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; Solute carrier family 7 member 8; solute carrier family 8 (cationic amino acid transporter, y+ system), member 7

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Gene Aliases: AA408822; LAT2; Lat4; LPI-PC1; SLC7A8

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UniProt ID: (Human) Q9UHI5, (Mouse) Q9QXW9, (Rat) Q9WVR6

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Entrez Gene ID: (Human) 23428, (Mouse) 50934, (Rat) 84551

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Function(s)
protein binding organic cation transmembrane transporter activity amino acid transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity antiporter activity toxin transporter activity peptide antigen binding amine transmembrane transporter activity
Process(es)
cellular amino acid metabolic process transport amino acid transport response to toxic substance organic cation transport neutral amino acid transport L-amino acid transport leukocyte migration metal ion homeostasis toxin transport L-alpha-amino acid transmembrane transport amino acid transmembrane transport amine transport transmembrane transport cation transmembrane transport
It has to be done as per old AB suggested Products section.
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