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OriGene

SCARB1 Monoclonal Antibody (OTI1F3), TrueMAB™

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite SCARB1 Monoclonal Antibody (OTI1F3), TrueMAB™

  • Antibody Testing Data (3)
SCARB1 Antibody in Immunocytochemistry (ICC/IF)
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SCARB1 Antibody in Immunocytochemistry (ICC/IF)
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SCARB1 Antibody (TA507135) in ICC/IF

Anti-SCARB1 mouse monoclonal antibody (TA507135) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SCARB1(RC210264). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SCARB1 Antibody in Immunocytochemistry (ICC/IF)
SCARB1 Antibody in Western Blot (WB)
SCARB1 Antibody in Western Blot (WB)

Product Details

TA507135

Applications
Tested Dilution
Publications

Western Blot (WB)

1:4,000
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1F3

Immunogen

Full length human recombinant protein of human SCARB1 produced in HEK293T cell.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen-like 1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; scavenger receptor b1; Scavenger receptor class B member 1; scavenger receptor class B type III; scavenger receptor class B, member 1; SR-BI; SRB1

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Gene Aliases: CD36L1; CLA-1; CLA1; HDLQTL6; SCARB1; SR-BI; SRB1

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UniProt ID: (Human) Q8WTV0

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Entrez Gene ID: (Human) 949

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Function(s)
lipopolysaccharide binding virus receptor activity phosphatidylserine binding lipopolysaccharide receptor activity transporter activity protein binding 1-phosphatidylinositol binding high-density lipoprotein particle binding low-density lipoprotein particle binding apolipoprotein binding apolipoprotein A-I binding protein homodimerization activity high-density lipoprotein particle receptor activity
Process(es)
endothelial cell proliferation androgen biosynthetic process cholesterol catabolic process receptor-mediated endocytosis positive regulation of endothelial cell migration positive regulation of triglyceride biosynthetic process positive regulation of cholesterol storage regulation of phosphatidylcholine catabolic process phospholipid transport lipopolysaccharide transport lipopolysaccharide-mediated signaling pathway detection of lipopolysaccharide cholesterol efflux high-density lipoprotein particle remodeling low-density lipoprotein particle clearance high-density lipoprotein particle clearance vitamin transmembrane transport wound healing lipoprotein metabolic process cholesterol homeostasis blood vessel endothelial cell migration recognition of apoptotic cell reverse cholesterol transport adhesion of symbiont to host viral entry into host cell regulation of phagocytosis intestinal absorption positive regulation of nitric-oxide synthase activity triglyceride homeostasis cholesterol import
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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