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  • S100B Antibodies

Abnova

S100B Monoclonal Antibody (1D4)

View all (97) S100B antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite S100B Monoclonal Antibody (1D4)

  • Antibody Testing Data (2)
S100B Antibody in ELISA (ELISA)
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S100B Antibody in ELISA (ELISA)
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S100B Antibody (H00006285-M51) in ELISA

Detection limit for recombinant GST tagged S100B is 0.03 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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S100B Antibody in Western Blot (WB)
S100B Antibody in ELISA (ELISA)
S100B Monoclonal Antibody (1D4)

Product Details

H00006285-M51

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

0.03 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1D4

Immunogen

S100B (NP_006263.1, 1 a.a. approximately 92 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE

Target Information

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein, beta (neural); S100 protein beta chain

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Gene Aliases: NEF; S100; S100-B; S100B; S100beta

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UniProt ID: (Human) P04271

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Entrez Gene ID: (Human) 6285

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Function(s)
calcium ion binding protein binding zinc ion binding identical protein binding protein homodimerization activity S100 protein binding tau protein binding calcium-dependent protein binding RAGE receptor binding
Process(es)
axonogenesis central nervous system development learning or memory memory cell proliferation positive regulation of cell proliferation regulation of cell shape positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response regulation of neuronal synaptic plasticity astrocyte differentiation response to glucocorticoid response to methylmercury long-term synaptic potentiation cellular response to hypoxia negative regulation of skeletal muscle cell differentiation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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