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  • Primary Antibodies ›
  • RXFP2 Antibodies

Invitrogen

RXFP2 Polyclonal Antibody

View all (9) RXFP2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RXFP2 Polyclonal Antibody

  • Antibody Testing Data (4)
RXFP2 Antibody in Immunocytochemistry (ICC/IF)
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RXFP2 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 4

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RXFP2 Antibody (PA5-102246) in ICC/IF

Immunocytochemistry analysis of RXFP2 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with RXFP2 polyclonal antibody (Product # PA5-102246) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RXFP2 Antibody in Immunocytochemistry (ICC/IF)
RXFP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RXFP2 Antibody in Western Blot (WB)
RXFP2 Antibody in Western Blot (WB)
RXFP2 Polyclonal Antibody

Product Details

PA5-102246

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RXFP2(Accession Q8WXD0), corresponding to amino acid residues E121-N171.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2851663

Product Specific Information

Antibody detects endogenous levels of total RXFP2.

Target Information

The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G protein coupled receptor affecting testicular descent; G protein-coupled receptor 106; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; INSL3 receptor; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2; Relaxin receptor 2; relaxin/insulin-like family peptide receptor 2

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Gene Aliases: Gpcr; GPR106; GREAT; INSL3R; LGR8; LGR8.1; RXFP2; RXFPR2

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UniProt ID: (Human) Q8WXD0, (Mouse) Q91ZZ5

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Entrez Gene ID: (Human) 122042, (Mouse) 140498, (Rat) 363866

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Function(s)
G-protein coupled receptor activity protein-hormone receptor activity peptide hormone binding signal transducer activity
Process(es)
oocyte maturation signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway negative regulation of cell proliferation male gonad development positive regulation of cAMP biosynthetic process negative regulation of apoptotic process adenylate cyclase-modulating G-protein coupled receptor signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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