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  • Primary Antibodies ›
  • RUNX1 Antibodies

Abnova

RUNX1 Monoclonal Antibody (4E7)

View all (44) RUNX1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RUNX1 Monoclonal Antibody (4E7)

  • Antibody Testing Data (4)
RUNX1 Antibody in Immunocytochemistry (ICC/IF)
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RUNX1 Antibody in Immunocytochemistry (ICC/IF)
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RUNX1 Antibody (H00000861-M05) in ICC/IF

Immunofluorescence of monoclonal antibody to RUNX1 on HeLa cell. Antibody concentration is 10 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RUNX1 Antibody in Immunocytochemistry (ICC/IF)
RUNX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RUNX1 Antibody in Western Blot (WB)
RUNX1 Antibody in ELISA (ELISA)
RUNX1 Monoclonal Antibody (4E7)

Product Details

H00000861-M05

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL
-

Immunocytochemistry (ICC/IF)

10 µg/mL
-

ELISA (ELISA)

1 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

4E7

Immunogen

RUNX1 (NP_001001890.1, 210 a.a. approximately 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: RVSPHHPAPT PNPRASLNHS TAFNPQPQSQ MQDTRQIQPS PPWSYDQSYQ YLGSIASPSV HPATPISPGR ASGMTTLSAE LSSRLSTAPD LTAFSDPRQF P

Target Information

RUNX1 belongs to the mammalian RUNX family of DNA binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac and placenta. RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow and peripheral blood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Acute myeloid leukemia 1 protein; AML-1; aml1 oncogene; AML1-EVI-1 fusion protein; CBF-alpha 2; CBF-alpha-2; Core-binding factor subunit alpha-2; core-binding factor, runt domain, alpha subunit 2; Oncogene AML-1; OTTHUMP00000108697; OTTHUMP00000108700; OTTHUMP00000108702; PEA2-alpha B; PEBP2-alpha B; Polyomavirus enhancer-binding protein 2 alpha B subunit; RUN1; Runt-related transcription factor 1; RUNX1/ZNF687 fusion; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; transcription factor

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Gene Aliases: AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha; RUNX1

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UniProt ID: (Human) Q01196

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Entrez Gene ID: (Human) 861

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Function(s)
regulatory region DNA binding RNA polymerase II regulatory region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protein binding ATP binding
Process(es)
ossification chondrocyte differentiation transcription from RNA polymerase II promoter hemopoiesis positive regulation of granulocyte differentiation positive regulation of interleukin-2 production positive regulation of angiogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter peripheral nervous system neuron development hematopoietic stem cell proliferation
It has to be done as per old AB suggested Products section.
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