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  • Primary Antibodies ›
  • RSPO1 Antibodies

OriGene

RSPO1 Monoclonal Antibody (OTI2F10), TrueMAB™

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite RSPO1 Monoclonal Antibody (OTI2F10), TrueMAB™

  • Antibody Testing Data (1)
RSPO1 Antibody in Western Blot (WB)
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RSPO1 Antibody in Western Blot (WB)
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RSPO1 Antibody (TA804531) in WB

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RSPO1 (RC217921, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RSPO1. Positive lysates LY422005 (100 µg) and LC422005 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RSPO1 Antibody in Western Blot (WB)
RSPO1 Monoclonal Antibody (OTI2F10), TrueMAB™

Product Details

TA804531

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI2F10

Immunogen

Human recombinant protein fragment corresponding to amino acids 21-263 of human RSPO1 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ40906; hRspo1; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1

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Gene Aliases: CRISTIN3; RSPO; RSPO1

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UniProt ID: (Human) Q2MKA7

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Entrez Gene ID: (Human) 284654

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Function(s)
G-protein coupled receptor binding receptor binding protein binding heparin binding
Process(es)
positive regulation of protein phosphorylation regulation of receptor internalization Wnt signaling pathway positive regulation of Wnt signaling pathway positive regulation of canonical Wnt signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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