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  • RSPO1 Antibodies

Invitrogen

RSPO1 Monoclonal Antibody (OTI1C3)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RSPO1 Monoclonal Antibody (OTI1C3)

  • Antibody Testing Data (2)
RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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RSPO1 Antibody (MA5-26690) in IHC (P)

Immunohistochemistry was performed on paraffin-embedded human colon tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a RSPO1 monoclonal antibody (Product # MA5-26690). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RSPO1 Antibody in Western Blot (WB)
RSPO1 Monoclonal Antibody (OTI1C3)

Product Details

MA5-26690

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1C3

Immunogen

Human recombinant protein fragment corresponding to amino acids 21-263 of RSPO1 produced in E.coli
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2725275

Target Information

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ40906; hRspo1; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1

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Gene Aliases: CRISTIN3; RSPO; RSPO1

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UniProt ID: (Human) Q2MKA7

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Entrez Gene ID: (Human) 284654

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Function(s)
G-protein coupled receptor binding receptor binding protein binding heparin binding
Process(es)
positive regulation of protein phosphorylation regulation of receptor internalization Wnt signaling pathway positive regulation of Wnt signaling pathway positive regulation of canonical Wnt signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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