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  • RSPO1 Antibodies

Invitrogen

RSPO1 Polyclonal Antibody

View all (16) RSPO1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite RSPO1 Polyclonal Antibody

  • Antibody Testing Data (8)
RSPO1 Antibody in Immunocytochemistry (ICC/IF)
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RSPO1 Antibody in Immunocytochemistry (ICC/IF)
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RSPO1 Antibody (PA5-20749) in ICC/IF

Immunofluorescent analysis of 4% paraformaldehyde-fixed human spleen labeling RSPO1 with RSPO1 Polyclonal Antibody (Product # PA5-20749) at 5 µg/mL, followed by goat anti-rabbit IgG secondary antibody at 1:500 dilution (green) with Phylloidin staining (red) and DAPI staining (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RSPO1 Antibody in Immunocytochemistry (ICC/IF)
RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RSPO1 Antibody in Western Blot (WB)
RSPO1 Antibody in Western Blot (WB)
RSPO1 Antibody in Western Blot (WB)
RSPO1 Antibody in Western Blot (WB)
RSPO1 Polyclonal Antibody

Product Details

PA5-20749

Applications
Tested Dilution
Publications

Western Blot (WB)

1-2 µg/mL
-

Immunocytochemistry (ICC/IF)

5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A 16 amino acid peptide from near the amino terminus of human RSPO1.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11152354

Product Specific Information

A suggested positive control is rat spleen tissue lysate.

PA5-20749 can be used with blocking peptide PEP-0863.

Target Information

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cristin-3; Cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1; thrombospondin type 1 domain containing gene Rspondin

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Gene Aliases: CRISTIN3; R-spondin; RSPO; RSPO1; Rspondin

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UniProt ID: (Human) Q2MKA7, (Mouse) Q9Z132

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Entrez Gene ID: (Human) 284654, (Mouse) 192199

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Function(s)
G-protein coupled receptor binding receptor binding protein binding heparin binding
Process(es)
positive regulation of protein phosphorylation regulation of receptor internalization Wnt signaling pathway positive regulation of Wnt signaling pathway positive regulation of canonical Wnt signaling pathway male meiosis regulation of gene expression response to stimulus canonical Wnt signaling pathway positive regulation of non-canonical Wnt signaling pathway regulation of male germ cell proliferation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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