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  • Primary Antibodies ›
  • RFC2 Antibodies

Invitrogen

RFC2 Polyclonal Antibody

View all (31) RFC2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RFC2 Polyclonal Antibody

  • Antibody Testing Data (5)
RFC2 Antibody in Immunocytochemistry (ICC/IF)
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RFC2 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 5

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RFC2 Antibody (PA5-56169) in ICC/IF

Immunofluorecent analysis of RFC2 in human cell line U-2 OS using RFC2 Polyclonal Antibody (Product # PA5-56169). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RFC2 Antibody in Immunocytochemistry (ICC/IF)
RFC2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RFC2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RFC2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RFC2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RFC2 Polyclonal Antibody

Product Details

PA5-56169

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RFC2. Recombinant protein control fragment (Product #RP-92618).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2646483

Product Specific Information

Immunogen sequence: PAPAFSKAPG SAGHYELPWV EKYRPVKLNE IVGNEDTVSR LEVFAREGNV PNIIIAGPPG TGKTTSILCL ARALLGPALK DAMLELNASN D

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Target Information

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: A1 40 kDa subunit; Activator 1 40 kDa subunit; Activator 1 subunit 2; Activator 1 subunit C2; MGC3665; replication factor C (activator 1) 2, 40kDa; Replication factor C 40 kDa subunit; Replication factor C subunit 2; replication factor C, 40 kDa; RF-C 40 kDa subunit; RFC40

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Gene Aliases: 2610008M13Rik; 40kDa; AI326953; Recc2; RFC2; RFC40

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UniProt ID: (Human) P35250, (Mouse) Q9WUK4, (Rat) Q641W4

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Entrez Gene ID: (Human) 5982, (Mouse) 19718, (Rat) 116468

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Function(s)
DNA clamp loader activity protein binding ATP binding enzyme binding single-stranded DNA-dependent ATPase activity nucleotide binding DNA binding molecular_function
Process(es)
telomere maintenance via recombination DNA replication transcription-coupled nucleotide-excision repair nucleotide-excision repair, DNA incision, 5'-to lesion nucleotide-excision repair, DNA gap filling translesion synthesis nucleotide-excision repair, DNA incision error-prone translesion synthesis DNA damage response, detection of DNA damage error-free translesion synthesis positive regulation of DNA-directed DNA polymerase activity regulation of signal transduction by p53 class mediator DNA-dependent DNA replication biological_process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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