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Proteintech
RBM15 Monoclonal Antibody (4A1A4)
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Product Details
66059-1-IG
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
Immunogen sequence: SSSRDRYNS DNDRSSRLLL ERPSPIRDRR GSLEKSQGDK RDRKNSASAE RDRKHRTTAP TEGKSPLKKE DRSDGSAPST STASSKLKSP SQKQDGGTAP VASASPKLCL AWQGMLLLKN SNFPSNMHLL QGDLQVASSL LVEGSTGGKV AQLKITQRLR LDQPKLDEVT RRIKVAGPNG YAILLAVPGS SDSRSSSSSA ASDTATSTQR PLRNLVSYLK QKQAAGVISL PVGGNKDKEN TGVLHAFPPC EFSQQFLDSP AKALAKSEED YLVMIIVRGF GFQIGVRYEN KKRENLALTL L (677-977 aa encoded by BC006397)
Target Information
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; RNA-binding motif protein 15; RNA-binding protein 15
Gene Aliases: OTT; OTT1; RBM15; SPEN
UniProt ID: (Human) Q96T37
Entrez Gene ID: (Human) 64783
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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