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Invitrogen
RBM15 Polyclonal Antibody
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FIGURE: 1 / 2
RBM15 Antibody (PA5-92321) in IHC (P)
Product Details
PA5-92321
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Immunogen sequence: EHRYQQQYLQ PLPLTHYELV TDAFGHRAPD PLRGARDRTP PLLYRDRDRD LYPDSDWVPP PPPVRERSTR TAATSVPAYE PLDSLDRRRD GWSLDRDRGD RDLPSSRDQP RKRRLPEESG GRHLDRSPES DRPRKRHCAP SPDRSPELSS SRDRYNSDND RSSRLLLERP SPIRDRRGSL EKSQGDKRDR KNSASAERDR KHRTTAPTEG KSPLKKEDRS DGSAPSTSTA SSKLKSPSQK QDGGTAPVAS A; Positive Samples: HL-60, HepG2, 293T, Jurkat, Mouse thymus, Mouse spleen; Cellular Location: Nucleus, Nucleus membrane, Nucleus speckle, Peripheral membrane protein, nucleoplasm
Target Information
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; putative RNA-binding protein 15; RNA-binding motif protein 15; RNA-binding protein 15
Gene Aliases: C230088J01Rik; Kiaa4257; mKIAA1438; OTT; OTT1; RBM15; SPEN
UniProt ID: (Human) Q96T37, (Mouse) Q0VBL3
Entrez Gene ID: (Human) 64783, (Mouse) 229700
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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