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  • RBM15 Antibodies

Abnova

RBM15 Polyclonal Antibody, MaxPab™

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Cite RBM15 Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (1)
RBM15 Antibody in Western Blot (WB)
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RBM15 Antibody in Western Blot (WB)
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RBM15 Antibody (H00064783-B01P) in WB

Western Blot analysis of RBM15 expression in transfected 293T cell line by RBM15 MaxPab polyclonal antibody. Lane 1: RBM15 transfected lysate(59.84 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RBM15 Antibody in Western Blot (WB)

Product Details

H00064783-B01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

10-100 µg/mL
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RBM15 (AAI03661.1, 1 a.a. approximately 544 a.a) full-length human protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MSHRAKLAMS GKIIIRNPIK IGYGKATPTT RLWVGGLGPW VPLAALAREF DRFGTIRTID YRKGDSWAYI QYESLDAAHA AWTHMRGFPL GGPDRRLRVD FADTEHRYQQ QYLQPLPLTH YELVTDAFGH RAPDPLRGAR DRTPPLLYRD RDRDLYPDSD WVPPPPPVRE RSTRTAATSV PAYEPLDSLD RRRDGWSLDR DRGDRDLPSS RDQPRKRRLP EESGGRHLDR SPESDRPRKR HCAPSPDRSP ELSSSRDRYN SDNDRSSRLL LERPSPIRDR RGSLEKSQGD KRDRKNSASA ERDRKHRTTA PTEGKSPLKK EDRSDGSAPS TSTASSKLKS PSQKQDGGTA PVASASPKLC LAWQGMLLLK NSNFPSNMHL LQGDLQVASS LLVEGSTGGK VAQLKITQRL RLDQPKLDEV TRRIKVAGPN GYAILLAVPG SSDSRSSSSS AASDTATSTQ RPLRNLVSYL KQKQAAGVIS LPVGGNKDKE NTGVLHAFPP CEFSQQFLDS PAKALAKSEE DYLVMIIVRA KLVEQRMKIW NSKL

Target Information

May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; RNA binding motif protein 15; RNA-binding motif protein 15; RNA-binding protein 15

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Gene Aliases: OTT; OTT1; RBM15; SPEN

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UniProt ID: (Human) Q96T37

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Entrez Gene ID: (Human) 64783, (Rat) 684233

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Function(s)
nucleotide binding nucleic acid binding protein binding poly(A) RNA binding
Process(es)
mRNA splicing, via spliceosome patterning of blood vessels positive regulation of transcription of Notch receptor target viral process negative regulation of myeloid cell differentiation negative regulation of transcription, DNA-templated spleen development ventricular septum morphogenesis placenta blood vessel development negative regulation of transcription from RNA polymerase II promoter
It has to be done as per old AB suggested Products section.
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