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  • Primary Antibodies ›
  • RbAp46 Antibodies

OriGene

RBBP7 Monoclonal Antibody (OTI5A4), TrueMAB™

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Cite RBBP7 Monoclonal Antibody (OTI5A4), TrueMAB™

  • Antibody Testing Data (11)
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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RBBP7 Antibody (TA503667) in IHC (P)

Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-RBBP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503667) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RBBP7 Antibody in Western Blot (WB)
RBBP7 Antibody in Western Blot (WB)
RBBP7 Monoclonal Antibody (OTI5A4), TrueMAB™

Product Details

TA503667

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI5A4

Immunogen

Full length human recombinant protein of RBBP7 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.84 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G1/S transition control protein-binding protein RbAp46; Histone acetyltransferase type B subunit 2; Histone-binding protein RBBP7; Nucleosome-remodeling factor subunit RBAP46; RBBP-7; retinoblastoma binding protein 7; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46; retinoblastoma-binding protein RbAp46

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Gene Aliases: RBAP46; RBBP7

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UniProt ID: (Human) Q16576

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Entrez Gene ID: (Human) 5931

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Function(s)
RNA binding histone deacetylase activity protein binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter DNA replication transcription, DNA-templated multicellular organism development cell proliferation histone deacetylation negative regulation of cell growth CENP-A containing nucleosome assembly negative regulation of gene expression, epigenetic response to steroid hormone cellular heat acclimation regulation of signal transduction by p53 class mediator
It has to be done as per old AB suggested Products section.
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