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  • RARB Antibodies

Abnova

RARB Monoclonal Antibody (1F7)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RARB Monoclonal Antibody (1F7)

  • Antibody Testing Data (1)
RARB Antibody in ELISA (ELISA)
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RARB Antibody in ELISA (ELISA)
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RARB Antibody (H00005915-M01) in ELISA

Detection limit for recombinant GST tagged RARB is approximately 0.1 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RARB Antibody in ELISA (ELISA)
RARB Monoclonal Antibody (1F7)

Product Details

H00005915-M01

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

1F7

Immunogen

RARB (AAH60794, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Product may be used with Sandwich ELISA (Recombinant protein).

Immunogen sequence: MFDCMDVLSV SPGQILDFYT ASPSSCMLQE KALKACFSGL TQTEWQHRHT AQSIETQSTS SEELVPSPPS PLPPPRVYKP CFVCQDKSSG YHYGVSACEG

Target Information

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: HBV-activated protein; hepatitis B virus activated protein; Nuclear receptor subfamily 1 group B member 2; RAR beta; RAR-b; RAR-beta; RAR-Beta2; RAR-Beta4; RAR-epsilon; retinoic acid; retinoic acid receptor; Retinoic acid receptor beta; retinoic acid receptor, beta polypeptide

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Gene Aliases: HAP; MCOPS12; NR1B2; RARB; RARbeta1; RRB2

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UniProt ID: (Human) P10826

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Entrez Gene ID: (Human) 5915

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding DNA binding steroid hormone receptor activity retinoic acid receptor activity drug binding zinc ion binding protein complex binding retinoid X receptor binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter ureteric bud development glandular epithelial cell development outflow tract septum morphogenesis retinal pigment epithelium development growth plate cartilage development transcription initiation from RNA polymerase II promoter signal transduction positive regulation of cell proliferation negative regulation of cell proliferation striatum development regulation of myelination negative regulation of chondrocyte differentiation embryonic hindlimb morphogenesis multicellular organism growth positive regulation of apoptotic process negative regulation of apoptotic process steroid hormone mediated signaling pathway positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter embryonic eye morphogenesis retinoic acid receptor signaling pathway embryonic digestive tract development ventricular cardiac muscle cell differentiation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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