Invitrogen

RAPGEF3 Recombinant Rabbit Monoclonal Antibody (5A7K7)

View all (21) RAPGEF3 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
RAPGEF3 Recombinant Rabbit Monoclonal Antibody (5A7K7)

Product Details

MA5-35451

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5A7K7

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 824-923 of human Epac1/RAPGEF3 (O95398)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849352

Product Specific Information

Immunogen sequence: FIHEGNHTLV ENLINFEKMR MMARAARMLH HCRSHNPVPL SPLRSRVSHL HEDSQVARIS TCSEQSLSTR SPASTWAYVQ QLKVIDNQRE LSRLSRELEP

Target Information

Gene ontology (GO) annotation includes small GTPase mediated signal transduction. Target protein binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 9330170P05Rik; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI); EPAC 1; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; MGC21410; Rap guanine nucleotide exchange factor (GEF) 3; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

View more View less

Gene Aliases: 2310016P22Rik; 9330170P05Rik; bcm910; CAMP-GEFI; CGEF1; EPAC; EPAC1; HSU79275; RAPGEF3

View more View less

UniProt ID: (Human) O95398, (Rat) Q9Z1C8, (Mouse) Q8VCC8

View more View less

Entrez Gene ID: (Human) 10411, (Rat) 59326, (Mouse) 223864

View more View less

Function(s)
guanyl-nucleotide exchange factor activity protein binding Rap guanyl-nucleotide exchange factor activity protein domain specific binding cAMP binding ion channel binding cAMP-dependent protein kinase regulator activity nucleotide binding
Process(es)
angiogenesis Rap protein signal transduction positive regulation of peptidyl-serine phosphorylation negative regulation of syncytium formation by plasma membrane fusion positive regulation of GTPase activity positive regulation of angiogenesis regulation of protein kinase activity positive regulation of protein export from nucleus positive regulation of stress fiber assembly positive regulation of syncytium formation by plasma membrane fusion establishment of endothelial barrier cellular response to cAMP positive regulation of protein acetylation regulation of actin cytoskeleton reorganization regulation of histone H3-K9 acetylation regulation of protein phosphorylation positive regulation of protein phosphorylation small GTPase mediated signal transduction positive regulation of smooth muscle cell migration positive regulation of ATPase activity negative regulation of collagen biosynthetic process intracellular signal transduction positive regulation of cell size positive regulation of transcription from RNA polymerase II promoter positive regulation of binding positive regulation of calcium ion transport negative regulation of cell death positive regulation of actin cytoskeleton reorganization signal transduction brain development cell proliferation negative regulation of cardiac muscle cell apoptotic process cAMP-mediated signaling spinal cord development positive regulation of cAMP catabolic process response to nicotine cellular response to drug regulation of insulin secretion artery development cellular response to transforming growth factor beta stimulus liver regeneration positive regulation of GTP binding positive regulation of calcium ion transmembrane transport positive regulation of hydrogen:potassium-exchanging ATPase activity cellular response to L-dopa dorsal root ganglion development
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support