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  • RAP Antibodies

Progen

RAP Monoclonal Antibody (7F1)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RAP Monoclonal Antibody (7F1)

RAP Monoclonal Antibody (7F1)

Product Details

61068PROGEN

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20
-

Immunohistochemistry (Frozen) (IHC (F))

1:20
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

7F1

Immunogen

Human Rap
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.5% BSA

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute lyophilized product with 1 mL distilled water.

7F1 reacts with the 39 kDa RAP protein, which is cosynthesized with human LRP/a2MW (low density lipoprotein receptor-related protein/a2-macro-globulin receptor). It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and a2-macroglobulin-proteinase complexes to LRP/a2MW.

Target Information

Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 39 kDa receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein; Alpha-2-MRAP; low density lipoprotein receptor-related protein associated protein 1; Low density lipoprotein receptor-related protein-associated protein 1; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1); RAP

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Gene Aliases: A2MRAP; A2RAP; alpha-2-MRAP; HBP44; LRPAP1; MRAP; MYP23; RAP

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UniProt ID: (Human) P30533

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Entrez Gene ID: (Human) 4043

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Function(s)
asialoglycoprotein receptor activity protein binding heparin binding lipase binding receptor antagonist activity low-density lipoprotein particle receptor binding unfolded protein binding very-low-density lipoprotein particle receptor binding
Process(es)
protein folding receptor-mediated endocytosis negative regulation of very-low-density lipoprotein particle clearance vesicle-mediated transport negative regulation of protein binding extracellular negative regulation of signal transduction negative regulation of beta-amyloid clearance
It has to be done as per old AB suggested Products section.
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