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  • RANK (CD265) Antibodies

Invitrogen

RANK (CD265) Monoclonal Antibody (D13)

View all (43) RANK (CD265) antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite RANK (CD265) Monoclonal Antibody (D13)

  • Antibody Testing Data (3)
RANK (CD265) Antibody in Western Blot (WB)
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RANK (CD265) Antibody in Western Blot (WB)
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RANK (CD265) Antibody (MA5-43899) in WB

Western blot analysis of RANK (CD265) in Rat Kidney lysate using RANK (CD265) Monoclonal Antibody (D13) (Product # MA5-43899) at a dilution of 3 µg/mL. Secondary antibody used is HRP-Goat anti-Mouse IgG polyclonal antibody at a dilution of 0.2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RANK (CD265) Antibody in Western Blot (WB)
RANK (CD265) Antibody in Western Blot (WB)
RANK (CD265) Antibody in Western Blot (WB)
RANK (CD265) Monoclonal Antibody (D13)

Product Details

MA5-43899

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-2 µg/mL
-

Immunohistochemistry (IHC)

5-20 µg/mL
-

Immunocytochemistry (ICC/IF)

5-20 µg/mL
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

D13

Immunogen

Val330-Lys615 (Accession Q9Y6Q6), with N-terminal His Tag
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912831

Target Information

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD265; loss of heterozygosity, 18, chromosomal region 1; ODFR; Osteoclast differentiation factor receptor; Paget disease of bone 2; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

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Gene Aliases: CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; RGD1563614; TNFRSF11A; TRANCER

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UniProt ID: (Human) Q9Y6Q6

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Entrez Gene ID: (Human) 8792, (Rat) 498206

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Function(s)
receptor activity transmembrane signaling receptor activity tumor necrosis factor-activated receptor activity protein binding cytokine binding metal ion binding molecular_function
Process(es)
ossification adaptive immune response multicellular organism development response to radiation programmed cell death osteoclast differentiation response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway response to cytokine response to tumor necrosis factor positive regulation of JUN kinase activity lymph node development positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity circadian temperature homeostasis mammary gland alveolus development response to interleukin-1 positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling monocyte chemotaxis inflammatory response signal transduction cell-cell signaling positive regulation of cell proliferation regulation of apoptotic process apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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