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  • RANK (CD265) Antibodies

Invitrogen

RANK (CD265) Polyclonal Antibody

View all (43) RANK (CD265) antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite RANK (CD265) Polyclonal Antibody

  • Antibody Testing Data (2)
RANK (CD265) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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RANK (CD265) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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RANK (CD265) Antibody (PA5-80145) in IHC (P)

Immunohistochemistry analysis of RANK (CD265) on paraffin-embedded human mammary cancer tissue. Sample was incubated with RANK (CD265) polyclonal antibody (Product# PA5-80145). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RANK (CD265) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
RANK (CD265) Antibody in Western Blot (WB)
RANK (CD265) Polyclonal Antibody

Product Details

PA5-80145

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human RANK (29-44aa QIAPPCTSEKHYEHLG).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2747259

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - IHC: Human Mammary Cancer Tissue.

Target Information

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD265; loss of heterozygosity, 18, chromosomal region 1; ODFR; Osteoclast differentiation factor receptor; Paget disease of bone 2; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

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Gene Aliases: CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TNFRSF11A; TRANCER

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UniProt ID: (Human) Q9Y6Q6

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Entrez Gene ID: (Human) 8792

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Function(s)
receptor activity transmembrane signaling receptor activity tumor necrosis factor-activated receptor activity protein binding cytokine binding metal ion binding
Process(es)
ossification adaptive immune response monocyte chemotaxis inflammatory response signal transduction cell-cell signaling positive regulation of cell proliferation response to radiation osteoclast differentiation response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway response to cytokine response to tumor necrosis factor regulation of apoptotic process positive regulation of JUN kinase activity lymph node development positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity circadian temperature homeostasis mammary gland alveolus development response to interleukin-1 positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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