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  • Primary Antibodies ›
  • RANK (CD265) Antibodies

Invitrogen

RANK Polyclonal Antibody

View all (43) RANK (CD265) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite RANK Polyclonal Antibody

Product Details

PA1-24722

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.2 µg/mL
-

ELISA (ELISA)

0.5-1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified recombinant human RANK extracelluar domain, expressed in mouse NSO cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2205343

Product Specific Information

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD265; loss of heterozygosity, 18, chromosomal region 1; ODFR; Osteoclast differentiation factor receptor; Paget disease of bone 2; receptor activator of NF-kappaB; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

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Gene Aliases: CD265; FEO; LOH18CR1; Ly109; mRANK; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TNFRSF11A; TRANCE-R; TRANCER

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UniProt ID: (Human) Q9Y6Q6, (Mouse) O35305

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Entrez Gene ID: (Human) 8792, (Mouse) 21934

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Function(s)
receptor activity transmembrane signaling receptor activity tumor necrosis factor-activated receptor activity protein binding cytokine binding metal ion binding
Process(es)
ossification adaptive immune response multicellular organism development programmed cell death osteoclast differentiation response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway response to cytokine response to tumor necrosis factor positive regulation of JUN kinase activity lymph node development positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity circadian temperature homeostasis mammary gland alveolus development response to interleukin-1 positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling monocyte chemotaxis inflammatory response signal transduction cell-cell signaling positive regulation of cell proliferation response to radiation regulation of apoptotic process apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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