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  • RANK (CD265) Antibodies

Bethyl Laboratories

RANK Polyclonal Antibody

View all (43) RANK (CD265) antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite RANK Polyclonal Antibody

  • Antibody Testing Data (1)
RANK Antibody in Immunoprecipitation (IP)
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RANK Antibody in Immunoprecipitation (IP)
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RANK Antibody (A303-808A) in IP

Detection of human RANK by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-RANK antibody (Product # A303-808A) used for IP at 6 µg/mg lysate. RANK was also immunoprecipitated by rabbit anti-RANK antibody A303-807A, which recognizes an upstream epitope. For blotting immunoprecipitated RANK, A303-807A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RANK Antibody in Immunoprecipitation (IP)
RANK Polyclonal Antibody

Product Details

A303-808A

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunoprecipitation (IP)

2-10 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 450 and 500 of Human Receptor activator of NF-KB.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD265; loss of heterozygosity, 18, chromosomal region 1; ODFR; Osteoclast differentiation factor receptor; Paget disease of bone 2; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

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Gene Aliases: CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TNFRSF11A; TRANCER

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UniProt ID: (Human) Q9Y6Q6

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Entrez Gene ID: (Human) 8792

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Function(s)
receptor activity transmembrane signaling receptor activity tumor necrosis factor-activated receptor activity protein binding cytokine binding metal ion binding
Process(es)
ossification adaptive immune response monocyte chemotaxis inflammatory response signal transduction cell-cell signaling positive regulation of cell proliferation response to radiation osteoclast differentiation response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway response to cytokine response to tumor necrosis factor regulation of apoptotic process positive regulation of JUN kinase activity lymph node development positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity circadian temperature homeostasis mammary gland alveolus development response to interleukin-1 positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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