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  • RAMP1 Antibodies

Invitrogen

RAMP1 Polyclonal Antibody

View all (11) RAMP1 antibodies

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Datasheet
Protocols
Questions & Answers

Cite RAMP1 Polyclonal Antibody

  • Antibody Testing Data (1)
RAMP1 Antibody in Western Blot (WB)
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RAMP1 Antibody in Western Blot (WB)
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RAMP1 Antibody (PA5-18958) in WB

Western blot analysis of RAMP1 using RAMP1 Polyclonal Antibody (Product # PA5-18958) (0.3 µg/mL) in staining of Rat Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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RAMP1 Antibody in Western Blot (WB)
RAMP1 Polyclonal Antibody

Product Details

PA5-18958

Applications
Tested Dilution
Publications

Western Blot (WB)

0.3-1 µg/mL
-
Product Specifications

Species Reactivity

Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (DYQSKRTEGIV) corresponding to the C-terminus amino acids of Ramp1 (aa 144-148).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984135

Product Specific Information

This antibody is predicted to react with human and mouse based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

Target Information

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC38240; receptor (calcitonin) activity modifying protein 1; Receptor activity-modifying protein 1

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Gene Aliases: Ramp1

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UniProt ID: (Rat) Q9JJ74

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Entrez Gene ID: (Rat) 58965

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Function(s)
G-protein coupled receptor binding receptor activity calcitonin receptor activity protein transporter activity coreceptor activity calcitonin receptor binding protein heterodimerization activity
Process(es)
angiogenesis calcium ion transport intracellular protein transport signal transduction G-protein coupled receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway protein transport positive regulation of cAMP biosynthetic process receptor internalization positive regulation of protein glycosylation protein localization to plasma membrane
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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