Invitrogen

RAGE Recombinant Rabbit Monoclonal Antibody (005)

Advanced Verification
View all (26) RAGE antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
RAGE Recombinant Rabbit Monoclonal Antibody (005)

Product Details

MA5-30062

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

005

Immunogen

Recombinant Mouse RAGE/AGER protein (Met1-Ala342)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2785849

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This antibody has specificity for Mouse RAGE/AGER.

Target Information

Able to phosphorylate several exogenous substrates and to undergo autophosphorylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Advanced glycosylation end product-specific receptor; advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; RAGE-4 ORF3; receptor for advanced glycation end-products variant 20; Receptor for advanced glycosylation end products; sRAGE

View more View less

Gene Aliases: AGER; RAGE; SCARJ1

View more View less

UniProt ID: (Human) Q15109

View more View less

Entrez Gene ID: (Human) 177, (Rat) 81722

View more View less

Function(s)
receptor activity transmembrane signaling receptor activity protein binding identical protein binding S100 protein binding advanced glycation end-product receptor activity high mobility group box 1 binding
Process(es)
response to hypoxia negative regulation of protein phosphorylation positive regulation of protein phosphorylation negative regulation of endothelial cell proliferation inflammatory response negative regulation of cell adhesion JAK-STAT cascade brain development glycoprotein metabolic process response to fructose positive regulation of autophagy negative regulation of endothelial cell migration positive regulation of gene expression positive regulation of epithelial to mesenchymal transition positive regulation of fibroblast migration response to activity positive regulation of smooth muscle cell migration lung development positive regulation of cell migration neuron projection development negative regulation of collagen biosynthetic process response to vitamin A response to genistein negative regulation of osteoblast proliferation cellular response to drug positive regulation of apoptotic process positive regulation of JUN kinase activity positive regulation of neuron apoptotic process positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation regulation of inflammatory response positive regulation of inflammatory response induction of positive chemotaxis positive regulation of NF-kappaB transcription factor activity regulation of DNA binding response to methylglyoxal calcium ion homeostasis response to hyperoxia positive regulation of phagocytosis, engulfment transdifferentiation cellular response to hydrogen peroxide cellular response to glucose stimulus cellular response to fatty acid cellular response to organic cyclic compound protein localization to membrane response to selenite ion positive regulation of potassium ion transmembrane transporter activity positive regulation of neuron death positive regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process positive regulation of type B pancreatic cell apoptotic process regulation of T cell mediated cytotoxicity cell surface receptor signaling pathway response to wounding negative regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of activated T cell proliferation innate immune response regulation of CD4-positive, alpha-beta T cell activation positive regulation of dendritic cell differentiation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support