Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
RAB3IP/Rabin8 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
12321-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: GKIDVLQAE VAALKTLVLS SSPTSPTQEP LPGGKTPFKK GHTRNKSTSS AMSGSHQDLS VIQPIVKDCK EADLSLYNEF RLWKDEPTMD RTCPFLDKIY QEDIFPCLTF SKSELASAVL EAVENNTLSI EPVGLQPIRF VKASAVECGG PKKCALTGQS KSCKHRIKLG DSSNYYYISP FCRYRITSVC NFFTYIRYIQ QGLVKQQDVD QMFWEVMQLR KEMSLAKLGY FKEEL (21-254 aa encoded by B C015548)
Target Information
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: gene trap PAT 12; Rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250|UniProtKB:Q96QF0}; rabin 3; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein
Gene Aliases: B230311A06; Gtpat12; RAB3IP; RABIN3; RABIN8
UniProt ID: (Human) Q96QF0, (Rat) Q62739, (Mouse) Q68EF0
Entrez Gene ID: (Human) 117177, (Rat) 29885, (Mouse) 216363
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support