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Proteintech
QDPR Polyclonal Antibody
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Product Details
14908-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MAAAAAAGE ARRVLVYGGR GALGSRCVQA FRARNWWVAS VDVVENEEAS ASIIVKMTDS FTEQADQVTA EVGKLLGEEK VDAILCVAGG WAGGNAKSKS LFKNCDLMWK QSIWTSTISS HLATKHLKEG GLLTLAGAKA ALDGTPGMIG YGMAKGAVHQ LCQSLAGKNS GMPPGAAAIA VLPVTLDTPM NRKSMPEADF SSWTPLEFLV ETFHDWITGK NRPSSGSLIQ VVTTEGRTEL TPAYF (1-244 aa encoded by BC000576)
Target Information
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 6,7-dihydropteridine reductase; Dihydropteridine reductase; HDHPR; HPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1; short chain dehydrogenase/reductase family 33C, member 1; testis secretory sperm-binding protein Li 236P
Gene Aliases: 2610008L04Rik; D5Ertd371e; DHPR; PKU2; QDPR; SDR33C1
UniProt ID: (Human) P09417, (Rat) P11348, (Mouse) Q8BVI4
Entrez Gene ID: (Human) 5860, (Rat) 64192, (Mouse) 110391
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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